Natural products inspired drug discovery

Literature of the Week

Sep. 02 2017

Acc. Chem. Res., 2015, 48, 1021-1031.

Divergent Pathways in Metal Carbene Cascades

Presenter : James Herndon III


Presenter : Steven Schlitzer


Presenter : Eric Gardner


Sep. 09 2017

Org. Lett., ​2017, 19, 1638

Mechanism of the Week:

Total Synthesis of the Cyclic Dodecapeptides Wewakazole and Wewakazole B

Sep. 16 2017

Nat. Chem., 2017, 1-6.  DOI: 10.1038/NCHEM.2839

Every Saturday the Sharma Lab holds Literature Meetings where one participant per week reviews literature relevant to Organic and/or Medicinal Chemistry.  Prior to the presentation a "Mechanism of the Week" is solved in hopes of warming up the groups mechanistic problem solving skills after a long week of research.  On this page you will find the literature source and presentation that was presented each week along with the Mechanism of the Week and its solution.  If you are interested in attending this session please e-mail and she will get you connected

Practice Preliminary Exam

Presenter : Joe Stevens


Signal transduction in a covalent post-assembly
modification cascade

Aug. 26 2017

Org. Lett., 2017, 19, 3454-3457